The 30 Best Hotels in South Carolina

Ranked 1 out of 1,035 in the South Carolina region, as well as being 1 of 150 for hotels in Charleston.

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• “Beautiful hotel in perfect location with southern charm”
• “Pleasant.”
• See more reviews of French Quarter Inn

Ranked 2 out of 1,035 in the South Carolina region, as well as being 1 of 92 for hotels in Greenville.

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• “We will come back.”
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• See more reviews of Hotel Hartness

Ranked 3 out of 1,035 in the South Carolina region, as well as being 2 of 150 for hotels in Charleston.

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• “Southern hospitality with class!”
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• See more reviews of The Spectator Hotel

Ranked 4 out of 1,035 in the South Carolina region, as well as being 3 of 150 for hotels in Charleston.

• “Very cute place”
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• “Perfect!”
• See more reviews of The Pinch Charleston

Ranked 5 out of 1,035 in the South Carolina region, as well as being 4 of 150 for hotels in Charleston.

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• “We had an excellent stay at the Drury Plaza and look forward to staying there again.”
• “Amazing stay and will return”
• See more reviews of Drury Plaza Hotel North Charleston

Ranked 6 out of 1,035 in the South Carolina region, as well as being 1 of 197 for hotels in Myrtle Beach.

• “It was a pleasurable stay, but I feel that we should have gotten our room cleaned at least once during our stay we staye”
• “Great stay!!”
• “When I look for somewhere to stay this hotel is the perfect example. Very clean rooms and great customer service. I will”
• See more reviews of Hilton Grand Vacations Club Ocean Enclave Myrtle Beach

Ranked 7 out of 1,035 in the South Carolina region, as well as being 1 of 14 for hotels in Beaufort.

• “A relaxing stay in a dream location”
• “Perfect place to stay and feel relaxed. Owners were so nice and attentive and had time to chat and make sure that your s”
• “Excellent job”
• See more reviews of Cuthbert House

Ranked 8 out of 1,035 in the South Carolina region, as well as being 5 of 150 for hotels in Charleston.

• “Celebrated our 18th anniversary with our first ever trip to Charleston. The trip was amazing and we would highly recomme”
• “6 day stay in Charleston”
• “Had a wonderful stay. Would highly recommend it.”
• See more reviews of Hilton Club Liberty Place Charleston

Ranked 9 out of 1,035 in the South Carolina region, as well as being 6 of 150 for hotels in Charleston.

• “GREAT LOCATION, STAFF, FOOD, DRINKS, SMALL POOL”
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• “Excellent, would stay again.”
• See more reviews of Hotel Bennett Charleston

Ranked 10 out of 1,035 in the South Carolina region, as well as being 1 of 19 for hotels in Clemson.

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• See more reviews of The Shepherd Hotel Downtown Clemson

Ranked 11 out of 1,035 in the South Carolina region, as well as being 3 of 92 for hotels in Greenville.

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• See more reviews of Homewood Suites By Hilton Greenville Downtown

Ranked 12 out of 1,035 in the South Carolina region, as well as being 2 of 197 for hotels in Myrtle Beach.

• “We used to live in the area and always dined at the restaurant next to the resort. We enjoyed the lodge and the location”
• “Nice place to stay”
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• See more reviews of Willow Lodge

Ranked 13 out of 1,035 in the South Carolina region, as well as being 1 of 4 for hotels in Lake City.

• “Mini Trip”
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• “I would stay just to eat!!!”
• See more reviews of The Inn At The Crossroads

Ranked 14 out of 1,035 in the South Carolina region, as well as being 1 of 7 for hotels in Greer.

• “Great location to places to eat dinner, or just have a drink.”
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• See more reviews of Hampton Inn Greer Greenville, Sc

Ranked 15 out of 1,035 in the South Carolina region, as well as being 3 of 197 for hotels in Myrtle Beach.

• “If I get to return to Myrtle Beach this is where I’ll stay. Location was easy to attractions. 10-15 minutes from airport”
• “Its was wonderful I will be back”
• “Our stay was relaxing in a beautiful setting with great service from the staff we encountered.”
• See more reviews of SpringHill Suites by Marriott Myrtle Beach Oceanfront

Ranked 16 out of 1,035 in the South Carolina region, as well as being 7 of 150 for hotels in Charleston.

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• “Clean Comfortable and Convenient”
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• See more reviews of Harbourview Inn

Ranked 17 out of 1,035 in the South Carolina region, as well as being 2 of 12 for hotels in Conway.

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• “Very clean hotel and close to Coastal Carolina University”
• “Great location and value”
• See more reviews of Fairfield by Marriott Inn & Suites Coastal Carolina Conway

Ranked 18 out of 1,035 in the South Carolina region, as well as being 4 of 197 for hotels in Myrtle Beach.

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• “My stay was Amazing! Everything was perfect!”
• “This was the perfect place for my family of 5 to stay.”
• See more reviews of Marriott's OceanWatch Villas at Grande Dunes

Ranked 19 out of 1,035 in the South Carolina region, as well as being 1 of 9 for hotels in Lexington.

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• “It was amazing.”
• “Excellent hotel in a great location!”
• See more reviews of Hampton Inn & Suites Lexington

Ranked 20 out of 1,035 in the South Carolina region, as well as being 8 of 150 for hotels in Charleston.

• “10 out of 10 on every level.”
• “Great staff; super comfortable!!”
• “Wonderful experience”
• See more reviews of 86 Cannon Charleston - Adults Only

Ranked 21 out of 1,035 in the South Carolina region, as well as being 5 of 197 for hotels in Myrtle Beach.

• “Fantastic!!!! A home away from home!!!10/10 will definitely stay again!”
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• “The best place we’ve ever stayed”
• See more reviews of Holiday Inn Club Vacations Myrtle Beach Oceanfront

Ranked 22 out of 1,035 in the South Carolina region, as well as being 1 of 25 for hotels in Anderson.

• “Came for family reunion and even left the reunion early to enjoy the ammenties! WONDERFUL place, HIGHLY RECOMMEND !”
• “Great value and great location”
• “It was so clean and smell good.”
• See more reviews of Residence Inn by Marriott Anderson Clemson

Ranked 23 out of 1,035 in the South Carolina region, as well as being 9 of 150 for hotels in Charleston.

• “If in the area, we would stay there again !!”
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• See more reviews of Home2 Suites By Hilton Charleston Daniel Island, Sc

Ranked 24 out of 1,035 in the South Carolina region, as well as being 4 of 92 for hotels in Greenville.

• “Beautiful hotel.”
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• “Breakfast was fantastic.”
• See more reviews of SpringHill Suites by Marriott Greenville Downtown

Ranked 25 out of 1,035 in the South Carolina region, as well as being 1 of 16 for hotels in Santee.

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• “2025 End of Summer Treck”
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• See more reviews of Fairfield Inn & Suites Santee

Ranked 26 out of 1,035 in the South Carolina region, as well as being 1 of 41 for hotels in Florence.

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• “Place was clean and smelled fresh on arrival.”
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• See more reviews of Staybridge Suites - Florence Center by IHG

Ranked 27 out of 1,035 in the South Carolina region, as well as being 6 of 197 for hotels in Myrtle Beach.

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• “If you’re looking for a relaxing time with family in a quiet area this is the hotel to stay in.”
• See more reviews of Hilton Grand Vacations Club Ocean 22 Myrtle Beach

Ranked 28 out of 1,035 in the South Carolina region, as well as being 7 of 197 for hotels in Myrtle Beach.

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• “The room was very clean and it smelled good too.”
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• See more reviews of Hilton Grand Vacations Club Anderson Ocean Myrtle Beach

Ranked 29 out of 1,035 in the South Carolina region, as well as being 1 of 91 for hotels in Columbia.

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• “Beautiful decoration design, clean, comfortable and very...”
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• See more reviews of Hotel Trundle

Ranked 30 out of 1,035 in the South Carolina region, as well as being 2 of 16 for hotels in Santee.

• “It was nice however a bit expensive”
• “This property is a winner!”
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• See more reviews of Hampton Inn Santee-I-95